Rapid elevation of transferrin saturation and serum hepcidin concentration in hemodialysis patients after intravenous iron infusion.
نویسندگان
چکیده
Natalia Kitsati,1 Dimitrios Liakos,2 Eleni Ermeidi,3 Michalis D. Mantzaris,1 Spyros Vasakos,4 Eleni Kyratzopoulou,5 Petros Eliadis,5 Emilios Andrikos,2 Elisavet Kokkolou,2 Georgios Sferopoulos,2 Avgi Mamalaki,5 Konstantinos Siamopoulos,3 and Dimitrios Galaris1 1Laboratory of Biological Chemistry, University of Ioannina Medical School, Ioannina; 2Nephrology Clinic, Hatzikosta Regional Hospital, Ioannina; 3Department of Nephrology, University of Ioannina Medical School, Ioannina; 4Biochemical Laboratory, Hatzikosta Regional Hospital, Ioannina; 5Laboratory of Molecular Biology and Immunobiotechnology, Hellenic Pasteur Institute, Athens, Greece
منابع مشابه
بررسی میزان تأثیر اسید آسکوربیک وریدی در اصلاح آنمی بیماران مبتلا به نارسایی کلیه تحت درمان همودیالیز
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BACKGROUND/AIM [corrected] Hepcidin may play a pathogenetic role in iron metobolism disorders. The aim of this study was to determine the correlation between hepcidin concentration and parameters of iron metabolism in patients with different stage of chronic kidney disease (CKD). METHODS The study involved 104 patients with CKD: 64 on hemodialysis (HD) and 40 patients in pre-dialysis stadium ...
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BACKGROUND Optimal iron levels in patients on hemodialysis are currently unknown, and a higher level than that for the healthy population is usually set for such patients considering the use of erythropoiesis-stimulating agents or the occurrence of chronic inflammation. However, excessive iron causes oxidative stress and impairment of its utilization by cells. Therefore we investigated the rela...
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ورودعنوان ژورنال:
- Haematologica
دوره 100 3 شماره
صفحات -
تاریخ انتشار 2015